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A protein made by your body that destroys foreign matter | |
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A substance present on our white blood cells that has the capacity to trigger an immune response | |
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White blood cell that produces antibodies and signals T cells and other cells that there is a problem | |
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The presence of viable bacteria in circulating blood* | Merck Manual |
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Protein with sugars attached to one or more amino acids |  WikiPedia |
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(human leukocyte antigens) system – a genetically determined series of markers (antigens) present on human white blood cells (leukocytes) and on tissues that are important in histocompatibility | |
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A medication that reduces the extent and degree of an immune response |
HealthAtoZ |
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A host response to the presence of micro-organisms or tissue invasion by microorganisms.* | WikiPedia |
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Presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention. |
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The systemic inflammatory response to infection. In association with infection, manifestations of sepsis are the same as those previously defined for SIRS. It should be determined whether they are a direct systemic response to the presence of an infectious process and represent an acute alteration from baseline in the absence of other known causes for such abnormalities.* |
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A subset of severe sepsis (SIRS) and defined as sepsis (SIRS) induced hypotension despite adequate fluid resuscitation along with the presence of perfusion abnormalities that may include, but are not limited to, lactic acidosis, oliguria, or an acute alteration in mental status. Patients receiving inotropic or vasopressor agents may no longer be hypotensive by the time they manifest hypoperfusion abnormalities or organ dysfunction, yet they would still be considered to have septic (SIRS) shock.* |
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Sepsis (SIRS) associated with organ dysfunction, hypoperfusion, or hypotension. Hypoperfusion and perfusion abnormalities may include, but are not limited to, lactic acidosis, oliguria, or an acute alteration in mental status. |
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The systemic inflammatory response to a wide variety of severe clinical insults, manifested by two or more of the following conditions:
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White blood cells (lymphocyte) that play a primary role in host defense against pathogens but can also be activated to attack oneself in autoimmune disease. There are T helper cells that activate the immune system through cytokine release and cytotoxic T cells that actually kill infected cells. | |
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Cells in the blood that fight infection. Your body produces a number of different immune system cells, such as T cells, B cells, and macrophages that help protect against invading pathogens, but can sometimes turn on your own body and attack it. |
*ACCP/SCCM Consensus Conference Definitions
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